Franklin has a great style of presentation, and i felt it. Necrotizing sialometaplasia ns is a benign disease showing inflammatory response which occurs in minor salivary glands mimicking a malignant lesion both clinically as well as histopathologically. Fascitis necrotizante tratamiento pdf cura fascitis. The cause is local ischemia producing infarction of salivary acini. Aug 23, 2011 necrotizing sialometaplasia is a benign, selflimiting and rare inflammatory disease which, on clinical and histological examination, mimics malignant neoplasms. Although entirely benign and requiring no treatment. Necrotizing sialometaplasia of major salivary glands. Necrotizing sialometaplasia ns is a benign, ulcerative lesion, usually located towards the back of the hard palate. Necrotizing sialometaplasia wikipedia republished wiki 2. A case of sialometaplasia of the soft palate is reported in a 2yearold girl 3 months after she had an adenoidectomy.
Necrotizing sialometaplasia as a cause of a nonulcerated. Sialometaplasia definition at, a free online dictionary with pronunciation, synonyms and translation. The vast majority 80% of cases affect the minor salivary glands of the palate, while other sites include gum behind the lower wisdom teeth retromolar pad, lip, tongue and cheek. Often painless, the condition is selflimiting and should heal in 610 weeks. Surgical management of necrotizing sialometaplasia of. Necrotizing sialometaplasia is a rare, benign inflammatory disease of the minor mucous salivary glands usually caused by glandular ischemia or trauma, that can mimic malignancy, but has a selflimiting character. Necrotizing sialometaplasia was first described in 1973 by abrams, melrose and howell1. Necrotizing sialometaplasia affects the salivary glands. Necrotizing sialometaplasia ns is a benign, self limiting inflammatory reaction of salivary gland tissue which may mimic squamous cell carcinoma or mucoepidermoid carcinoma both clinically and histologically and can lead to unnecessary surgical approach. Oral examination revealed a nodule consisting of two lobules on the right. The major importance of this condition is the danger of misdiagnosis, because it may clinically and histologically mimic a malignancy. Necrotizing sialometaplasia is a rare inflammatory necrotizing reactive process that can involve minor and major salivary glands.
In 1973, abrams et al first reported this condition. The ensuing inflammation causes squamous metaplasia of ducts and hyperplasia of the surface stratified squamous epithelium. The clinical and histopathologic features of necrotizing sialometaplasia often simulate those of malignancies such as squamous cell carcinoma or salivary gland malignancy. Necrotising sialometaplasia is extremely rare there are barely 200 cases reported in the world literature. Lisa franklin is an oral pathologist who presented a forensics lecture to the residency. Surgical management of necrotizing sialometaplasia of palate. A further five cases were reported the following year by dunlap and barker. Necrotizing sialometaplasia nsm is an uncommon inflammatory condition that affects salivary glands.
How to search for text inside multiple pdf files at once. Necrotizing sialometaplasia a diagnostic conundrum dental. Seekfast also lets you easily search for your terms in various file types including pdf. Dec 17, 2015 necrotizing sialometaplasia nsm is a rare benign, inflammatory disease of both major and minor salivary glands, although more commonly reported in the minor glands of the palate. Necrotizing sialometaplasia international journal of. We report the case of a healthy 25yearold caucasian woman with a threeweek history of a painless. The characteristic clinical presentation can perplex the clinician and may be mistaken for a malignant neoplasm, such as mucoepidermoid carcinoma, as well as. Download and install the software on your computer. The lesions heal on their own with or without biopsy. Jul 11, 2016 necrotizing sialometaplasia is a rare, benign, selflimiting, necrotizing process involving the minor salivary glands, mainly the mucoserous glands of the hard palate. Necrotizing sialometaplasia of the hard palate in a patient. Mar 29, 2018 necrotizing sialometaplasia ns is a nonneoplastic inflammatory condition of the salivary glands.
Necrotizing sialometaplasia of the palate j canadian dental association 2007. The vast majority of cases occur on the posterior lateral hard palate. It is thought to be caused by ischemic necrosis death of tissue due to lack of blood supply of minor salivary glands in response to trauma. Physicians should be aware of its clinical and histological traits in order to avoid unnecessary disfiguring surgery. Necrotizing sialometaplasia necrotizing sialometaplasia is. This pathological lesion was first reported in 1973. Sialometaplasia necrotizante, glandula salivar menor, lesiones orales. Necrotizing sialometaplasia a diagnostic conundrum. Information and translations of sialometaplasia, necrotizing in the most comprehensive dictionary definitions resource on the web. A rare site of socalled necrotizing sialometaplasia. Dental practitioners should be aware of the possible causes of intraoral swellings in both children and adults. Sialometaplasia of the soft palate in a 2yearold girl cases journal. The appearance of some conditions in children may differ from their characteristic appearance in adults. Necrotizing sialometaplasia is a rare, benign, selflimiting, necrotizing process involving the minor salivary glands, mainly the mucoserous glands of the hard palate.
It is considered by some authors to be a distinct entity 1,2 and by others to be part of the spectrum of necrotizing sialometaplasia ns. Definition of sialometaplasia, necrotizing in the dictionary. A sn foi descrita pela primeira vez em 1973 por abrans et al. Jun 23, 2014 necrotizing sialometaplasia ns is a benign, selflimiting inflammatory reaction of salivary gland tissue which may mimic squamous cell carcinoma or mucoepidermoid carcinoma, both clinically and histologically, that creates diagnostic dilemma leading to unwarranted aggressive surgery. It predominantly affects salivary tissue and usually involves the palate, although it has. Necrotizing sialometaplasia in the setting of acute and chronic sinusitis. The diagnosis is difficult and can be dont only through a biopsy section as well as clinical history. Some predisposing factors such as smoking, use of alcohol, denture wearing, recent surgery, traumatic injuries. Sep 01, 2006 necrotizing sialometaplasia is a benign inflammatory process that involves the minor salivary glands, primarily those of the hard palate.
Mucus gland infarct with squamous epithelial metaplasia in the lung. Necrotizing sialometaplasia ns is a nonneoplastic inflammatory condition of the salivary glands. Necrotizing sialometaplasia ns is a benign, ulcerative lesion, usually located towards the. To the best of our knowledge, only 22 cases of sans have been reported, mostly on salivary palatal. Pdf necrotizing sialometaplasia ns is a selflimiting inflammatory disease, that involves salivary glands, more frequently the minor ones. Download fulltext pdf sialometaplasia necrotizante. Necrotizing sialometaplasia radiology reference article. The lesion occurs due to vascular ischemia caused by trauma. Some predisposing factors such as smoking, use of alcohol, denture wearing, recent surgery. What links here related changes upload file special pages permanent link page.
Sialometaplasia definition of sialometaplasia by medical. Mar 26, 2011 necrotizing sialometaplasia ns is a benign, self limiting inflammatory reaction of salivary gland tissue which may mimic squamous cell carcinoma or mucoepidermoid carcinoma both clinically and histologically and can lead to unnecessary surgical approach. This relatively rare condition holds diagnostic importance because of its ambiguous clinical and histopathological presentation that can be misdiagnosed clinically as neoplasia. This selflimiting benign lesion is easily confused with malignant tumors.
It is thought to be the result of an ischemic event of the vasculature supplying the salivary gland lobules. The reason for biopsy is to rule out cancer from their worrisome clinical presentation. Necrotizing sialometaplasia is a completely benign lesion that is most likely caused by ischemia secondary to trauma examples of causes could be dental injection or hot liquid burn. Once windows has finished indexing your pdfs and their contents, youll be able to search for text inside multiple pdf files at once use seekfast to search pdf files. Case report open access necrotizing sialometaplasia as a. A case of necrotizing sialometaplasia ns is presented in a female patient, who initially presented as a suspected head and neck malignancy. We report the case of a healthy 25yearold caucasian woman with a threeweek history of a painless lump on her hard palate. Gland tissue ischaemia has been proposed as the aetiology. Epidemiology most patients are more than 40 years of age, with. Necrotizing sialometaplasia nsm is a rare benign, inflammatory disease of both major and minor salivary glands, although more commonly reported in the minor glands of the palate. Oral examination revealed a nodule consisting of two lobules on the right side that measured 2. Mostly it occurs in the palate and also salivary glands. Necrotizing sialometaplasia ns is a benign, selflimiting inflammatory reaction of salivary gland tissue which may mimic squamous cell carcinoma or mucoepidermoid carcinoma, both clinically and histologically, that creates diagnostic dilemma leading to unwarranted aggressive surgery.
Entre estas encontramse patologias infecciosas, autoimunes e linfoproliferativas. Necrotizing sialometaplasia definition of necrotizing. Necrotizing sialometaplasia of hard palate a case report. It appears as an aggressive looking lesion in an adult possibly resembling squamous cell carcinoma and mucoepidermoid carcinoma. The lesions are characterized histologically by an extensive necrosis of the salivary gland tissue together with squamous metaplasia of the ducts. Necrotizing sialometaplasia is a reactive lesion of salivary gland origin. This pathological lesion was first reported in 1973 by abrams et al. Necrotizing sialometaplasia an important diagnosis. Necrotizing sialometaplasia necrotizing sialometaplasia. Necrotizing sialometaplasia is a benign inflammatory condition of the salivary gland remnants or elements, which is usually selflimiting.
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